Skin cancer is the most common form of cancer, with millions of cases per year in the U.S. alone. About one in five people in the U.S. will get skin cancer during their lifetime. These cancers are often diagnosed by removal of small amounts of skin from suspected cancers (biopsies). MOST biopsies… more
Nine in ten cancer deaths are linked to the spread (metastasis) of cancer from its original location to other parts of the body. HOW and WHY cancer cells move is a huge question. Some recent advances are shedding light on this mysterious, but deadly process. When treated with drugs or other… more
Tasmanian devils are known as ferocious predators. Maybe too ferocious!  Devils are threatened with extinction by a very unusual cancer, devil facial tumor disease (DFTD). Unlike almost all other cancers, DFTD spreads from animal to animal - it is transmitted when they fight and bite each other.… more
Researchers have joined an immune-boosting agent (CpG) and a tumor-targeting chemical (PIP) together to create a novel drug (PIP-CpG) to fight cancer. When injected directly into tumors or into animals with cancer, the PIP part of the chemical causes it to target cancer cells and the CpG part… more
Natural killer (NK) cells are an amazing part of the human immune system and have the potential to kill breast tumor cells. However, NK cells need a trigger for them to do so. Dr. Wei and his team from Clemson University came up with the idea of using a bifunctional protein to bridge the NK cells… more
Why does cancer kill? That is a surprisingly hard question to answer. When cancer spreads (metastasizes), the affected organs may not work as well, but that does not provide the whole answer. Work with tiny fruit flies may be helping to provide some answers to this question and also providing ways… more
Can cancer cells, or any cells, taste things? Not the way we do, but cells have proteins on their surface that act like antennas. These proteins (called receptors) receive signals from outside the cell and can cause the cells to change what it's doing. New research results provide some interesting… more
Cancer affects everyone, but not equally. There are many reasons for the differences seen in the numbers, kinds and outcomes of cancers in different groups of people. Some of the differences can be eliminated by taking an active role in preventing cancer and detecting it early. It is also important… more
Cancer develops when important genes become damaged. The targeted genes usually control things like whether or not a cell will reproduce, live or die. Those genes that normally provide a 'go' signal are called proto-oncogenes and those that act as 'stop' signals are called tumor suppressors. New… more
The White House has released a proclamation designating September National Ovarian Cancer month. Ovarian cancer is relatively rare, but because it has few early warning signs, it is often lethal. The American Cancer Society estimates that almost 14,000 women will die from ovarian cancer in the U.S… more
How can a rare gecko help us understand human skin cancer? It turns out that geckos get cancer too, and these particular geckos get a kind of skin cancer that's similar to some found in human. Lemon Frost leopard geckos are new. The breed arose from a rare genetic event (mutation) that causes the… more
Cancer researchers have many ways to study the biology of cancer and to find and test possible treatments. Examples include growing cancer cells grown in dishes, implanting cancer in animals and even creating three dimensional balls of human tissue known as organoids or tumoroids. However, the… more
Have you ever taken “Omega-3 fish oil” supplements? Fatty acids are essential for humans. For example, one type of omega-3 fatty acid called DHA (short for docosahexaenoic acid) helps make up body structures, including the brain and the eye. A team of researchers at the University of Louvain… more
Cancer patients may wonder if their disease or ongoing treatments may change how well the COVID-19 vaccine works and their body’s response to the vaccine. A study done in Israel helps to answer that question. The research included 102 patients with a mixture of cancer types and ongoing treatments… more
Our immune system is able to recognize and attack cancer. In fact, many cancers are recognized and eliminated before they become large enough to pose a problem. One thing that slows down the attack is the tangled and dense network of cable-like fibers surrounding cancer cells in tumors. It is… more
Cancer is often thought of as a modern disease. Increased numbers of cases has been linked to exposure to chemicals, pollution and the rise in the use of tobacco products. A study from Britain shows that cancer likely affected many more people than previously thought. The researchers examined the… more
The spread of cancer, metastasis, is the cause of 9 out of 10 cancer deaths. Unfortunately, there are currently no drugs that are effective in preventing metastasis. For many years, it was believed that cancer spread from the initial tumor only when the cancer cells had developed many new mutations… more
Since the discovery of the very first cancer-causing viruses and then the cancer-causing genes (oncogenes) they carried, research on the genes of cancer has focused on our chromosomes. Humans have 23 pairs of chromosomes that contain a total of about 20,000 genes. That is certainly a lot to study… more
Mesothelioma is a cancer caused by exposure to asbestos, a mineral. Currently, less than 1 in 10 patients with mesothelioma survive five years after diagnosis. New research using artificial intelligence to analyze genetic information from patients has shown that the development of the disease… more
Getting older is the single biggest risk factor for cancer. But WHY is that the case? It turns out that the genetic changes that ultimately lead to cancer can form MANY years before the cancer is detected. Researchers looking at an older (63 yr old) and a younger (34 yr old) patient with blood… more