A promising new cancer detection test is being tested at Johns Hopkins University. DELFI, which stands for DNA evaluation of fragments for early interception, detected 91% of cancer cases in a sample of 208 patients. DELFI would be more cost-effective than current cancer tests. DELFI is a blood… more
Many kinds of cancer are found more commonly in people who are obese. The reasons for this are not completely understood. A new study from the Trinity College Dublin sheds more light on the problem. Cancer cells can be recognized and killed by immune cells called, quite appropriately, natural… more
Many exciting new cancer treatments are designed to let the patient's own immune system kill their cancer cells. The results can be remarkable and have saved many lives already.  Two unusual cases show the power, and danger, of CAR-T cells, a type of immune-based cancer treatment. The treatments… more
As we advance our understanding of cancers such as gliomas, one thing is very clear.  Cancers are highly variable.  Even cancers of the same type (i.e. glioma) are not exactly the same in different patients. This variation poses a great challenge to the development of more efficient cancer… more
The discovery of the DNA-editing bacterial enzyme CRISPR-Cas9 created great excitement because of its potential for treating and even curing genetic diseases. Now a group of researchers from Karolinska Institute, University of Helsinki, and University of Cambridge, have found a potential problem… more
A new study has shown the flight attendants are at increased risk for several different kinds of cancer. Flying exposes the workers to higher levels of space radiation, disrupts their sleep patterns, and exposes them to potentially unsafe air. In response to this, an industry union (http://www.… more
Whatever the flavor - cherry, mango, or mint - vaping (or Juuling) is BAD news! One Juul pod contains as much nicotine as an entire pack of cigarettes. This makes them extremely addictive. Nicotine is a powerful drug and affects heart rate, breathing and other body functions. Vaping products are… more
As we age, our cells age too. Some of them stop dividing and enter a state of reduced activity called senescence.  Senescent cells can produce signals that lead to inflammation, aging and even cancer. New research has demonstrated that (at least in mice) killing senescent cells can lead to the… more
It is hard to overstate this. This. Is. Huge. A woman with previous incurable breast cancer has no evidence of disease 22 months after being treated with  a combination of immunotherapies. The patient had gone through many different kinds of chemotherapy but still had large tumors growing in her… more
Cancer patients have long been treated for the TYPE of cancer they have (breast, lung, prostate, etc.). Newer approaches are designed to look for drug targets that are common between cancer types.  The idea is to treat the cancer based on its genetic makeup, regardless of where it appears. The… more
The results of a large trial show that most women who are diagnosed with early stage breast cancer do not need to take chemotherapy. "The study found that for women with hormone receptor (HR)-positive, HER2-negative, axillary lymph node­–negative breast cancer, treatment with chemotherapy and… more
We’ve all heard it many times; everyone from our doctors to our friends says, “Keep your cholesterol in check, and avoid eating fatty foods.” In addition to increasing your risk for heart disease, cholesterol may also increase the rate at which cells in the intestine grow and divide, a… more
What is the link between gut bacteria and cancer treatment? A study reported in January 2018 has found that 'good' microbes in the gut make cancer immunotherapy work better. Researchers were specifically looking at an immune checkpoint inhibitor- an antibody that targets an immune-regulator protein… more
Although it is well known that chronic inflammation plays a major role in the growth and progression of cancers, physicians and researchers are still learning of exactly how chronic inflammation is causes cancer. According to a new study published by Dr. Karin et al. of University of California San… more
The identification of signals that indicate the presence of disease is challenging, but important.   These signals (called biomarkers) could hold the key to the early diagnosis of pancreatic cancer. Drs. Zaret and Petersen from the Penn Institute for Regenerative Medicine and Mayo Clinic,… more
As the director of a cancer education project, I frequently get questions from friends, family members and others about people diagnosed with cancer. Hopefully this advice will be helpful to others.  Note that I am not a medical doctor of any kind. I am a PhD. I do not give medical advice on cancer… more
Cancer survivors often go through many different treatments, including radiation and chemotherapy drugs.  These treatments are often successful in getting rid of cancer, but some negative effects can last a lifetime. The life expectancy for cancer survivors is 30% lower than those who have not had… more
New research from researchers at Mt. Sinai Medical Center may change the way we understand how cancer spreads (metastasizes).  The study looked at how very early breast cancer spreads. Even before a tumor was visible, changes in immune cells called macrophages lead to movement of breast cancer… more
A study of 650 Europeans followed for 10 years suggests that eating more fruits and vegetables, particularly tomatoes and apples may help keep the lungs healthy. Those people with increased intake of these foods showed better lung function, and it appears that the diet was able to help repair lung… more
So, e-cigarettes are supposed to help people quit smoking, right? The opposite may be true.  A study of 915 U.S. adults compared people who used e-cigarettes with those that didn't. E-cigarette users were much more likely to start smoking tobacco within 18 month. For those who did not vape, 10.2%… more