Bone metastasis occurs in many different types of cancer and can lead to pain and bone weakness. New research has determined that a signaling pathway known as the 'Notch' pathway is involved in activating bone-destroying cells (osteoclasts) and causing the production of proteins that enhance metastasis.
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Wikimedia Common http://upload.wikimedia.org/wikipedia/commons/3/31/Osteocyte_2.jpg
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