Newsroom

11/13/2010
Sequencing of DNA from 281 acute myeloid leukemia (AML) patients has identified a single gene that is associated with a worse prognosis.  The gene, DNMT3A, encodes a DNA methyltransferase, an enzyme that modifies DNA.  Patients with mutations in DNMT3A had a median survival of 12.3 months vs 41.1… more
11/13/2010
Results presented at an American Association of Cancer Research (AACR) conference showed that 90% of children living in households with smokers had detectable levels of tobacco-associated cancer-causing agents in their urine.  Ninety-five percent of the children had detectable levels of cotinine, a… more
11/13/2010
Prostate cancer that no longer responds to inhibitors of androgens, called 'castration resistant prostate cancer (CRPC)', tends to be more aggressive.  Comparison of the DNA of prostate cancers lead to the identification of a protein, N-cadherin, that is present at high levels in many of these… more
11/8/2010
Researchers at Yorkshire Cancer Research have developed a novel method of detecting small cancer growths.  The researchers use viruses to deliver a fluorescent jellyfish protein to the cancer cells.  The cells then glow red when exposed to a specific type of light.  The technique allows for the… more
11/8/2010
Tumors are complex mixtures of normal (stromal) cells and cancer cells. Researchers using mouse models have shown that stromal cells can block immune function.  The stromal cells were found to produce a protein, fibrobast activation protein-alpha (FAP), that inhibits the immune system.  When the… more
11/5/2010
Researchers from an international team have succeeded in keeping surgically removed prostate tissues, both normal and cancerous, alive and functional.  The new technique allows researchers to study cancer in a new way.  The cancer cells are still in their natural 'home'.  The new model could have… more
11/5/2010
Freeze dried black raspberries were shown to reduce colon cancer development in two different types of mice.  Each of the mouse types is susceptible to developing colon cancer, but for different reasons.  Each mouse strain is defective in a different way but the raspberry fed mice had changes in… more
11/4/2010
MIT researchers have shown that medicinal plants can be made to make new,  novel drugs.  The scientists introduced bacterial genes into a plant that naturally produces the a chemical (vinblastine) that is used to treat some forms of cancer.  The new genes gave the plants the ability to produce… more
11/4/2010
November is lung cancer awareness about and now lung cancer clinicians and others have something to celebrate. Despite the fact that lung cancer kills more people in the U.S. than breast, colorectal, pancreatic and prostate cancers combined, lung cancer screening options are limited. The results… more
11/4/2010
One of the keys to the success of cancer surgery is the removal of every cancer cell. Currently, the success of surgeries requires examination of the removed tissue. A new pen-like instrument may be able to help cancer surgeons make sure they succeed as they are operating.  Tumors are labeled with… more
11/2/2010
Our  immune system is constantly on the lookout for cells that are not acting normally.  Changes can occur due to infection with a virus or the conversion of a normal cell to a cancer cell.  Abnormal cells are killed by having holes 'punched' in their membranes.  The proteins that perform this… more
11/1/2010
Researchers at Wake Forest University have grown the first human liver in their laboratories.  The researchers started with animal livers and stripped away all the cells, leaving behind only the framework of the organ.  They then added human liver and blood vessel cells.  The small number of human… more
11/1/2010
A study conducted by the Japanese Public Health Center looked at the risk of breast cancer in ~54,000 women followed for 13.6 yrs.  They found no protective effects in women who consumed green tea.  Other researchers point out that the results hightlight the difficulties of performing population… more
10/29/2010
Liver cancer (hepatocellular carcinomaor HCC) is responsible for hundreds of thousands of deaths each year.  Even with the advent of targeted drugs like sorafenib, most patients with HCC do not have a viable treatment option. One possible target for treatments are changes in the genome that are… more
10/29/2010
A study of 773 young colon cancer patients and 1660 healthy individuals showed that those people whose chromosomes were unusually long or short were more likely to develop colon cancer.  Specifically, the researchers looked at the very tips of the chromosomes, areas called telomeres.  Telomeres act… more
10/28/2010
A European study of over 400,000 people found that consuming a wide variety of fruits and vegetables was associated with a decrease risk of lung cancer in active smokers.  After an average follow-up of 8.7 years, those indiviuals with a diet including a diversity of fruits and vegetables had a… more
10/28/2010
An analysis of the eating habits over 33,000 women was used to estimate the impact of dieatary acrylamide intake on breast cancer risk.  Acrylamide is found in carbohydrate-rich foods cooked at high temperatures (i.e. french fries and potato chips).  It is also found in cigarette smoke.  The… more
10/27/2010
A Danish study following over 55,000 men and women for a period of about 10 years found that those who had healthy lifestyles were able to substantially lower their risk of developing colorectal cancer.  Activities monitored included physical activity, alcohol consumption, smoking, waist… more
10/26/2010
A Swedish study of 1167 men found that a single prostate specific antigen (PSA) test at age 60 was able to accurately predict which men were likely to develop aggressive prostate cancer.  The men were part of a large Swedish prevention study and were followed until age 85.  The results suggest that… more
10/25/2010
Triple negative breast cancer tends to occur in younger women and is more common in African American women. These cancers lack the estrogen receptor (ER), progesterone receptor (PR) and epidermal growth factor receptor (HER2). Triple negative cancer is harder to treat because the drugs targeted at… more