Quiz | CancerQuest

Inversions result in ____________.

A.

The formation of many copies of a specific region of the affected chromosome

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B.

The breakage and movement of chromosome fragments

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C.

More than one copy of each gene on a chromosome

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D.

A genetic change that involves the loss or gain of entire chromosomes

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E.

Segments of DNA being released from a chromosome then re-inserted in the opposite orientation

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A genetic change that involves the loss or gain of entire chromosomes leads to _____.

A.

Inversion

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B.

Duplication

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C.

Deletion

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D.

Aneuploidy

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E.

Recombination

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The process of repetitive replication of a segment of a chromosome is known as ______.

A.

Nonsense Mutation

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B.

Missense Mutation

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C.

Gene Amplification

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D.

Frameshift Mutation

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E.

Spontaneous Mutation

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Because they arise from a single precursor cell, tumor cells are genetically identical.

True

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False

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Cancer Drug Resistance

Which of the following can not cause mutations?

A.

Chemical mutagens found in the environment

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B.

Transcription errors by RNA polymerase

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C.

Products produced by cells involved in chronic inflammation

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D.

Oxygen radicals produced by mitochondria

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E.

Radiation from the sun

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Nonsense mutations occur when:

A.

The new codon causes an incorrect amino acid to code for an incorrect protein

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B.

The loss or gain of 1 or 2 nucleotides that affects the coding for a protein.

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C.

An alteration in sequence results in a new codon that causes the code to create an incomplete protein.

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D.

Chromosomes break, causing a loss of DNA

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E.

Genes in chromosome mutate and code for incorrect DNA

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Changes in DNA sequences during replication can lead to the following:

A.

Missense mutations

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B.

Nonsense mutations

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C.

Aneuploidy

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D.

a and b

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E.

a, b and c

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In order to cause a frame shift mutation, ______ must occur.

A.

The insertion of three nucleotides into the coding region

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B.

A substitution mutation leading the insertion of a U for a G

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C.

A missense mutation causing the insertion of a hydrophobic amino acid

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D.

A nonsense mutation leading to protein termination

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E.

One or two nucleotides must be inserted or deleted in the coding region

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The type of mutation that causes a single incorrect amino acid to be inserted into a protein is known as a _____.

A.

Nonsense mutation

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B.

Defense mutations

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C.

Consense mutation

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D.

Missense mutation

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E.

Antisense mutation

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DNA point mutations _____.

A.

Have no effect because of the redundancy of the nucleotide code.

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B.

Causes an incorrect amino acid, but no change in the overall protein.

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C.

Always leads to a nonfunctional protein.

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D.

Can lead to a nonfunctional protein or can have little effect depending on the position of the mutation.

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E.

Lead to the formation of an alternative protein structure, but the function of the protein doesn't change.

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