Interview with Dr. Jean-Pierre Issa

Dr. Jean-Pierre Issa
Department of Leukemia
The University of Texas M.D. Anderson Cancer Center

Dr. Issa's research focuses on the epigenetics of cancer. The term epigenetics refers to events that can change how a gene functions without changing the DNA sequence of the gene. The changes can be slight chemical modifications to the DNA itself or modifications to the the proteins in which the DNA is packaged. In this interview, Dr. Issa explains epigenetics and the way that epigenetic changes can influence cancer development. Epigenetic changes are also an important target for potential cancer drugs.

Questions and Answers

	About Jean-Pierre Issa(Time: 19 sec)
	How Dr. Issa Became Interested in Medical Oncology(Time: 1 min 50 sec)
	Understanding Epigenetics(Time: 3 min 30 sec)
	DNA Methylation and How it Affects Gene Expression(Time: 4 min 32 sec)
	The Importance of Epigenetics in the Origin of Cancer(Time: 4 min 41 sec)
	Parental Influence on Epigenetics Though Their Behavior(Time: 2 min 31 sec)
	Factors That Affect Epigenetics(Time: 2 min 58 sec)
	Epigenetics and Drug Research(Time: 2 min 14 sec)
	Dr. Issa's Current Research(Time: 1 min 32 sec)

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Last Modified: 10/08/2010

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