Chlorambucil (Leukeran®)
Drug Usage
Chlorambucil (Leukeran®) is an alkylating agent that is used to treat a variety
of cancer types.
Malignancies for which chlorambucil is use include:
- Chronic lymphocytic leukemia
- Lymphomas
- Hodgkin's disease
Chlorambucil is usually administered as an intravenous infusion or in tablet form.
Adverse Effects
Common side effects include:
- Bone marrow suppression
- Nausea and vomiting
- Diarrhea
- Oral ulcers
Less common side effects include tremors, twitching, seizures, other abnormal activity of the nervous system, and also changes in and allergic reactions of the skin.
Chlorambucil should not be taken by women who are pregnant and patients should not become pregnant while using this drug, as it may have harmful affects on the developing fetus. This drug may also have negative effects on fertility in the years following treatment.
Bone marrow depression is the most common toxicity associated with chlorambucil's usage. It is important to monitor the levels of white blood cells, platelets, and hemoglobin.
Search for current clinical trials involving chlorambucil.
| < Previous Page | << Previous Section | Next Section >> |
Next Page >
|
  |
|