Many chemotherapy drugs are highly toxic. During intravenous infusion, the drug may enter the area of injection (infusion) and cause tissue damage. Drugs can get into the tissues around the injection site because of leakage around the needle or they may actually leave the blood stream after they have been injected. The process by which drugs leave a blood vessel is called extravasation. The result is that healthy tissues in the area of the injection can become irritated or even severely damaged. The actual result is dependent on the type of drug and the amount that enters the area.(1)
Treatments for chemotherapy induced tissue damage:
Dexrazoxane (Totect®)
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