The stomach is a sac-like organ located between the esophagus and small intestine. The stomach aids in digestion and stores food. Anatomically, the stomach has been broken down into 5 different regions: cardia, fundus, body, antrum, and pylorus (see below). The stomach is also composed of 5 different tissue layers: mucosa, submucosa, muscularis, subserosa, and serosa. The more layers a cancer invades, the worse its prognosis.(1)

The stomach is also associated with an extensive lymphatic network. Cancer that has spread to the nearby lymphatics has a worse prognosis.(2)
Learn more about the lymphatic system.
Learn more about the lymphatic system and metastasis.